|
Diseases
Related to Bioaerosols |
Contagious Diseases: Many Viral and Bacterial Diseases |
Infection
Organisms must be viable. |
Transmission
Mode
Human to human.
Route of Infection
Through air or by contact. |
Agents
Viruses: cannot reproduce without hosts, may survive
on surfaces including ventilation or filtration. Bacteria (e.g., tuberculosis):
generally not found in building substrates. |
Risk
Factors
Genetic factors, lack of
immunity, dose, virulence of agents, environmental factors: Immune deficiency;
medications, substances abuse, etc. |
Evaluation
Diagnosis, epidemiology;
air/source sampling is ineffective.
Control
Avoid contact. |
|
Infections from Environmental Sources: Many Bacterial & Fungal
Diseases |
Infection
Organisms must be viable; may
also cause allergic/toxic response. |
Transmission
Mode
Environmental reservoirs; some
such as chlamydia and rickettsia are assoc. with vector carriers such as rodents or other
mammals.
Route of Exposure
Through air or by contact. |
Agents
Bacteria: Legionella
(Legionnaire's disease and Pontiac Fever); flavobacteria, etc., Fungi: histoplasma,
blastomyces, coccidioidomyces, Cryptococcus, Aspergillius, etc. |
Risk
Factors
Genetic
factors, lack of immunity, dose, virulence of agents, environmental factors. Immune
deficiency; medications, substance abuse, etc. |
Evaluation
Diagnosis, epidemiology; site observation, source
sampling; air sampling may be useful for Aspergillius and Pseudomonas, but difficult for
Legionella.
Control
Remove sources. |
|
Hypersensitivity: Asthma & Hay Fever |
Immune
Response
Diseases; agents of exposure
need not be alive. |
Transmission
Mode
Environmental reservoirs.
Route of Exposure
Inhalation.
|
Agents
Fungi (mostly spores), pollens,
arthropods (mites, roaches) mammals (cat and dog danders), etc. |
Risk
Factors
Genetic factors, sensitization,
antigenicity. |
Evaluation
Diagnosis, site observation
source sampling of reservoirs, air sampling.
Control
Remove sources, avoid allergens. |
|
Hypersensitivity: Hypersensitivity Pneumontis |
Immune
Response
Diseases; agents of exposure
need not be alive.
|
Transmission
Mode
Environmental reservoirs.
Route of Exposure
Inhalation.
|
Agents
Bacteria, actinomyces, fungi
(mostly spores), protozoa, proteins, biological organic dust. |
Risk
Factors
Host risk unknown, prolonged
and high levels of exposure, adjuvents, antigenicity. |
Evaluation
Diagnosis, source sampling of
reservoirs, air sampling.
Control
Remove sources, avoid allergens. |
|
Toxicoses:
Acute Toxicity, Immune Suppression, Cancer & Human Fever |
Direct
Cellular Effect
Toxins or carcinogens of
biological origin; exposure units need not be alive, and may linger, depending on chemical
stability; cancer is rare. |
Transmission
Mode
From environmental reservoirs,
either assoc. with organisms or discharge by organisms. |
Agents
Bacteria toxins: endotoxins and
exotoxins. Fungal toxins, mycotoxins, such as alfatoxins. |
Risk
Factors
Human response is constant;
toxicity, dose, immune suppressors.
|
Evaluation
Diagnosis, site observation
source sampling of organisms, air sampling to verify exposure
Control
Remove sources. |
Extracted from
Suggested Guidelines for Remediation of Damage from Sewage
Backflow into Buildings
An Environmental Protection Agency (EPA) Working Document
Michael A. Berry, Ph.D., Jeff Bishop, Claude Blackburn, Eugene C. Cole, Dr., Ph.D.,
William G. Ewald,
Terry Smith, Nathan Suazo, and Steve Swan
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